In-Vitro Toxicology Testing Market – Trends Forecast Till 2030

Market Snapshot

Market Overview

The global In Vitro Toxicology Testing Market size is projected to reach a CAGR of 10.8% from 2023-2030.

In vitro is the process that helps examine harmful chemicals over the isolated part of the organism. It is used to identify hazardous chemical substances and helps detect toxicity at the early stages of the development of new products, such as drugs, cosmetics, and food additives. In vitro, toxicity testing (IVTT) is mainly used for safety evaluation in drug development and also for ranking the chemicals according to their potency. The absorption, distribution, metabolism, excretion (ADME), dose-response, and threshold response of the drug can also be determined by in vitro toxicity testing.

The rise in the number of R&D procedures will act as a major driver accelerating the in-vitro toxicology testing market’s growth rate. Another significant factor resulting in the expansion of the market is the growing development of 3D cell culture. Furthermore, a ban on animal testing and rising environmental concerns are the major drivers that will enhance the growth of the market. Likewise, a rise the government funding for research along with favourable reimbursement policies for developing automated and technically advanced equipment for laboratory analysis will show a positive impact on the market’s growth rate. Growing healthcare expenditure, rapid urbanization, and a rise in the level of disposable incomes in developing and developed countries will influence the growth rate of the in-vitro toxicology testing market.

On the other hand, the rising number of toxicology databases and advancements in medical technology will provide beneficial opportunities for the in-vitro toxicology testing market growth. Adding to this high cost associated with testing and the scarcity of in vitro models to study complex endpoints are factors that will obstruct market growth.

The COVID-19 pandemic forced many companies in the global in vitro toxicity testing market to halt business operations for a short term to comply with new government regulations to curb the spread of the disease. This halt in operations directly impacts the revenue flow of the global in vitro toxicity testing market. In addition, there is a halt in the manufacturing of industrial products, owing to a lack of raw materials and manpower during the lockdown period. Further, no new consignments are received by companies that operate in this sector. Hence, a halt in industrial activities and lockdowns for several months has affected the global in vitro toxicity testing market and the market is anticipated to witness a slow recovery during the forecast period.

Delvens Industry Expert's Standpoint

Various novel techniques and fields are offering significant advancements in the comprehension of the biological responses of human tissues to chemical agents. These cutting-edge advancements are predicted to push forward the expansion of the in-vitro toxicology market growth throughout the projected duration.

Market Portfolio

Key Findings

• The technology segment is further segmented into Cell Culture Technology, High Throughput Technology, Molecular Imaging, and OMICS Technology. Cell culture technology dominated the market for in-vitro toxicology testing during the forecast period. It serves as an excellent model for examining toxic effects since it provides consistent samples and reproducible results, which enables early-stage detection of toxicity in the drug development process. Moreover, cell cultures are increasingly replacing animal testing, leading to its extensive application.
   
• The application segment is further fragmented into Systemic Toxicology, Dermal Toxicity, Endocrine Disruption, Ocular Toxicity, and Others. The systemic toxicology segment is anticipated to dominate the market for in-vitro toxicology testing during the forecast period. The development of multiple organ plates with simulated blood flow for assessing systemic toxicity drives the segment growth. Moreover, public and private organizations are taking initiatives for replacing animal testing with in-vitro techniques for acute systemic toxicity testing.

• Method segment is further segmented into Cellular assay, Biochemical Assay, In-Silico, and Ex-vivo. The cellular assay market is anticipated to dominate the market during the forecast period. This can be attributed to the wider availability of this technique for the pharmacokinetic profiling of drug products. Moreover, several pharmaceutical and biotechnological companies are essentially dependent on cellular assays for toxicity screening in the early stages of drug development.

• The end-user segment is further segmented into Pharmaceutical Industry, Cosmetics & Household Products, Academic Institutes and Research Laboratories, Diagnostics, Chemical Industry, and Food Industry. The pharmaceutical industry segment is anticipated to dominate the market during the forecast period. The high usage of toxicology testing in pharmacokinetic analysis of novel and generic modified pharmaceutical products results in the revenue growth of these toxicity testing assays. Moreover, the presence of several drug candidates in the pipeline is expected to drive the demand for in-vitro toxicology testing.

Regional Analysis

North America to Dominate the Market

• North America dominated the in-vitro toxicology testing market and accounted for the largest revenue share in 2021, owing to an increased focus of government bodies on drug discovery, a rise in healthcare expenditure, and the presence of adequate infrastructure for the growth and development of drug discovery technologies.
   
• Furthermore, strong regulatory guidelines pertaining to drug development and approval have boosted the adoption of services in the regional market for in-vitro toxicology testing.
   
• Government organizations in the Asia Pacific region are expected to drive the growth of in-vitro toxicology testing by promoting such methods. This is projected to result in the region witnessing the highest growth rate among all other regions.

Competitive Landscape

• Thermo Fisher Scientific
• Agilent Technologies
• Bio-Rad Laboratories
• Danaher Corporation
• Quest Diagnostics
• Merck KGaA
• Perkin Elmer, Inc.
• Laboratory Corporation of America Holdings
• Eurofins Scientific
• Charles River Laboratories International, Inc.
• Abbott
• Catalent, Inc.
• Evotec
• SGS SA
• GVK Biosciences
• Gentronix
• WuXi AppTec
• MB Research Laboratories
• BioIVT

Recent Developments

• In March 2022, Laboratory Corporation of America Holdings acquired AtlantiCare diagnostic clinical laboratory services.
   
• In September 2021, Laboratory Corporation of America Holdings Acquired Myriad Autoimmune’s Vectra Testing Business, an autoimmune business unit, including the Vectra rheumatoid arthritis (RA) assay.

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• Qualitative and quantitative data utilization to discover arrays of future growth from the market trends of leaders to market visionaries and then recognize the significant areas to compete in the future.
   
• In-depth analysis of the changing trends of the market by visualizing the historic and forecast year growth patterns.

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